Director Shareholding

AstraZeneca PLC
4 December 2001



DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

ASTRAZENECA PLC ANNOUNCES THAT, ON 3 DECEMBER 2001, MR J R SYMONDS, A DIRECTOR
OF THE COMPANY, ACQUIRED 272 OF THE COMPANY'S USD0.25 ORDINARY SHARES AT A
PRICE OF 2146P FOLLOWING THE EXERCISE OF AN OPTION UNDER THE COMPANY'S SAVINGS
RELATED SHARE OPTION SCHEME. MR SYMONDS' INTEREST IN THE ORDINARY SHARES OF
THE COMPANY HAS INCREASED TO 14,314 SHARES WHICH REPRESENTS LESS THAN 0.001
PER CENT OF THE NUMBER OF SHARES IN ISSUE. MR SYMONDS NOW HAS OPTIONS OVER
130,561 ORDINARY SHARES.




G H R MUSKER
COMPANY SECRETARY
4 DECEMBER 2001