Director Shareholding

AstraZeneca PLC
8 May 2002



DEALING BY DIRECTORS

COMPANIES ACT 1985 SECTION 324/329

WE HEREBY INFORM YOU THAT, ON 7 MAY 2002, MR J R SYMONDS, A DIRECTOR OF THE
COMPANY, SOLD 486 ASTRAZENECA PLC ORDINARY SHARES OF USD0.25 EACH AT 3130 PENCE
PER SHARE. THE SALE WAS MADE BY THE COMPANY ON BEHALF OF MR SYMONDS IN ORDER TO
MEET AN IMMEDIATE INCOME TAX LIABILITY ARISING ON THE RELEASE OF SHARES FROM THE
COMPANY'S EXECUTIVE SHARE RETENTION SCHEME.  FOLLOWING THIS SALE, MR SYMONDS HAS
A TOTAL INTEREST IN 13,828 ORDINARY SHARES, WHICH REPRESENTS APPROXIMATELY
0.0008 PER CENT OF THE NUMBER OF SHARES CURRENTLY IN ISSUE.





G H R MUSKER

COMPANY SECRETARY

8 MAY 2002



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