Director Shareholding

AstraZeneca PLC
26 March 2003

DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

WE HEREBY INFORM YOU THAT ON 25 MARCH 2003 THE FOLLOWING DIRECTORS OF
ASTRAZENECA PLC WERE GRANTED OPTIONS UNDER THE ASTRAZENECA SHARE OPTION PLAN.
THE OPTIONS ARE EXERCISABLE OVER THE COMPANY'S USD0.25 ORDINARY SHARES.

NAME OF DIRECTOR          NUMBER OF SHARES    EXERCISE PRICE    PERIOD WHEN EXERCISABLE  TOTAL NUMBER OF
                          OVER WHICH OPTION   PER SHARE                                  SHARES UNDER OPTION
                          IS GRANTED

T F W MCKILLOP            128,498             2231p             25.3.06-24.3.13          467,566
H L MOGREN                 65,551             2231p             25.3.06-24.3.13          269,976
J R SYMONDS                48,012             2231p             25.3.06-24.3.13          208,388


G H R MUSKER
COMPANY SECRETARY
26 MARCH 2003


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