Director Shareholding

AstraZeneca PLC
08 July 2003




DEALING BY DIRECTORS

COMPANIES ACT 1985 SECTIONS 324/329


WE HEREBY INFORM YOU THAT, ON 7 JULY 2003, SIR TOM MCKILLOP, A DIRECTOR OF THE
COMPANY, ACQUIRED AN INTEREST IN 61 ASTRAZENECA PLC ORDINARY SHARES OF USD0.25
EACH AT A PRICE OF 2439 PENCE PER SHARE.  THE INTEREST ARISES AS A RESULT OF THE
AUTOMATIC ANNUAL ACQUISITION OF ASTRAZENECA SHARES BY EMPLOYEES PARTICIPATING IN
THE COMPANY'S PARTNERSHIP SHARE ARRANGEMENTS.  PARTNERSHIP SHARES ARE ACQUIRED
AND HELD ON BEHALF OF PLAN PARTICIPANTS BY ASTRAZENECA EMPLOYEE SHARE TRUST
LIMITED UNDER THE TERMS OF THE ASTRAZENECA ALL EMPLOYEE SHARE PLAN, WHICH IS
OPEN TO ALL UK EMPLOYEES OF THE COMPANY.  FOLLOWING THIS ACQUISITION, SIR TOM
MCKILLOP HAS A TOTAL INTEREST IN 69,560 ORDINARY SHARES, WHICH REPRESENTS
APPROXIMATELY 0.004 PER CENT OF THE NUMBER OF SHARES CURRENTLY IN ISSUE.




G H R MUSKER
COMPANY SECRETARY
8 JULY 2003



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