Director Shareholding

AstraZeneca PLC
08 September 2003

DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTION 324/329

WE HEREBY INFORM YOU THAT WE WERE INFORMED TODAY BY JOE JIMENEZ, A DIRECTOR OF
THE COMPANY, THAT ON 5 SEPTEMBER 2003 HE PURCHASED 500 AMERICAN DEPOSITARY
SHARES OF THE COMPANY AT USD42.72 PER SHARE.   EACH AMERICAN DEPOSITARY SHARE
REPRESENTS ONE USD0.25 ORDINARY SHARE OF THE COMPANY. THIS REPRESENTS HIS TOTAL
INTEREST, WHICH IS APPROXIMATELY 0.00003 PER CENT OF THE ISSUED SHARE CAPITAL OF
THE COMPANY.


G H R MUSKER
COMPANY SECRETARY
8 SEPTEMBER 2003


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