Director Shareholding

AstraZeneca PLC
13 November 2003

DEALING BY DIRECTORS

COMPANIES ACT 1985 SECTIONS 324/329



WE HEREBY INFORM YOU THAT, ON 13 NOVEMBER 2003, SIR TOM MCKILLOP, A DIRECTOR OF
THE COMPANY BECAME BENEFICIALLY ENTITLED TO 1,378 ASTRAZENECA PLC ORDINARY
SHARES OF USD0.25 EACH.  THE SHARES WERE ALLOCATED TO SIR TOM MCKILLOP ON 16
NOVEMBER 2000 AND HAVE BEEN HELD IN TRUST SINCE THEN IN ACCORDANCE WITH THE
ARRANGEMENTS ANNOUNCED AT THAT TIME.  ON 13 NOVEMBER 2003 THE COMPANY SOLD 567
OF THE SAID SHARES AT A PRICE OF 2765 PENCE PER SHARE ON BEHALF OF SIR TOM
MCKILLOP IN ORDER TO MEET AN IMMEDIATE INCOME TAX LIABILITY ARISING ON THE
RELEASE OF THE SHARES.  FOLLOWING THIS SALE, SIR TOM MCKILLOP HAS A TOTAL
INTEREST IN 77,835 ORDINARY SHARES, WHICH REPRESENTS APPROXIMATELY 0.005 PER
CENT OF THE NUMBER OF SHARES CURRENTLY IN ISSUE.







G H R MUSKER

COMPANY SECRETARY

13 NOVEMBER 2003




                      This information is provided by RNS
            The company news service from the London Stock Exchange  ND

RDSBLBDBDDBGGXX