Director Shareholding

AstraZeneca PLC
29 March 2004

DEALING BY DIRECTORS

COMPANIES ACT 1985 SECTIONS 324/329



WE HEREBY INFORM YOU THAT ON 26 MARCH 2004 THE FOLLOWING DIRECTORS OF
ASTRAZENECA PLC WERE GRANTED OPTIONS UNDER THE ASTRAZENECA SHARE OPTION PLAN.
THE OPTIONS ARE EXERCISABLE OVER THE COMPANY'S USD0.25 ORDINARY SHARES.




NAME OF DIRECTOR       NUMBER OF SHARES     EXERCISE PRICE   PERIOD WHEN EXERCISABLE    TOTAL NUMBER OF
                       OVER WHICH OPTION IS PER SHARE                                   SHARES UNDER OPTION
                       GRANTED


T F W MCKILLOP         118,622              2529p            26.3.07-25.3.14            571,864
J R SYMONDS             44,049              2529p            26.3.07-25.3.14            252,437





G H R MUSKER
COMPANY SECRETARY
29 MARCH 2004




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