Directors' Dealings

AstraZeneca PLC
14 December 1999


TO: COMPANY ANNOUNCEMENTS OFFICE

DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

WE HEREBY INFORM YOU THAT ON 13 DECEMBER 1999 THE FOLLOWING DIRECTOR OF THE
COMPANY WAS GRANTED AN OPTION UNDER THE COMPANY'S 1994 EXECUTIVE SHARE OPTION
SCHEME.  THE OPTION IS EXERCISABLE OVER THE COMPANY'S USD0.25 ORDINARY SHARES.

NAME OF          NUMBER OF      EXERCISE     PERIOD WHEN         TOTAL NUMBER
DIRECTOR         SHARES UNDER   PRICE PER    EXERCISABLE         OF SHARES
                 OPTION         SHARE                            UNDER OPTION

H L MOGREN       49,108         2749P        13.12.02-12.12.09   49,108


FROM: G H R MUSKER
      COMPANY SECRETARY