Directors' Dealings

AstraZeneca PLC
3 December 1999


DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

WE HEREBY INFORM YOU THAT, ON 1 DECEMBER 1999, SIR DAVID BARNES, A DIRECTOR OF
THE COMPANY, ACQUIRED 287 OF THE COMPANY'S USD0.25 ORDINARY SHARES AT A PRICE
OF 1357P FOLLOWING THE EXERCISE OF AN OPTION UNDER THE COMPANY'S SAVINGS
RELATED SHARE OPTION SCHEME. SIR DAVID'S INTEREST IN THE ORDINARY SHARES OF
THE COMPANY HAS INCREASED TO 214,576  SHARES WHICH REPRESENTS APPROXIMATELY
0.012 PER CENT OF THE NUMBER OF SHARES IN ISSUE. SIR DAVID NOW HAS OPTIONS
OVER 144,031 ORDINARY SHARES.


G H R MUSKER
COMPANY SECRETARY
3 DECEMBER 1999