Directors' Dealings

AstraZeneca PLC
9 November 1999


TO: COMPANY ANNOUNCEMENTS

DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

WE HEREBY INFORM YOU THAT, ON 8 NOVEMBER 1999, SIR DAVID BARNES, A DIRECTOR OF
THE COMPANY, ACQUIRED 1,372 OF THE COMPANY'S USD0.25 ORDINARY SHARES AT A
PRICE OF 754P FOLLOWING THE EXERCISE OF AN OPTION UNDER THE COMPANY'S SAVINGS
RELATED SHARE OPTION SCHEME. SIR DAVID'S INTEREST IN THE ORDINARY SHARES OF
THE COMPANY HAS INCREASED TO 214,289  SHARES WHICH REPRESENTS APPROXIMATELY
0.012 PER CENT OF THE NUMBER OF SHARES IN ISSUE. SIR DAVID NOW HAS OPTIONS
OVER 144,318 ORDINARY SHARES.

FROM: G H R MUSKER
      COMPANY SECRETARY