Directors' Dealings

AstraZeneca PLC
17 March 2000


DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTIONS 324/329

WE HEREBY INFORM YOU THAT ON 16 MARCH 2000 THE FOLLOWING DIRECTORS OF
ASTRAZENECA PLC WERE GRANTED OPTIONS UNDER THE COMPANY'S 1994 EXECUTIVE SHARE
OPTION SCHEME.  THE OPTIONS ARE EXERCISABLE OVER THE COMPANY'S USD0.25
ORDINARY SHARES.

NAME OF          NUMBER OF      EXERCISE     PERIOD WHEN        TOTAL NUMBER
DIRECTOR         SHARES UNDER   PRICE PER    EXERCISABLE        OF SHARES
                 OPTION         SHARE                           UNDER OPTION

T F W MCKILLOP   22,108         2714P        16.3.03-15.3.10    164,792

H L MOGREN       24,871         2714P        16.3.03-15.3.10    111,459

M P PRAGNELL      9,580         2714P        16.3.03-15.3.10    116,089

A B T STAVLING   14,186         2714P        16.3.03-15.3.10     61,080

C E WILHELMSSON  17,686         2714P        16.3.03-15.3.10     68,346