Holding in Company

AstraZeneca PLC 22 January 2004 COMPANIES ACT 1985 SECTION 198 DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES ON 22 JAN 2004 WE WERE INFORMED BY THE CAPITAL GROUP COMPANIES, INC., A REGISTERED INVESTMENT MANAGER IN THE U.S., THAT ON 20 JAN 2004 ITS INTEREST IN THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC HAD INCREASED TO 256,568,628 SHARES (15.16 PER CENT OF THE CURRENT ISSUED ORDINARY CAPITAL) FROM THE PREVIOUSLY NOTIFIED LEVEL OF 240,060,302 SHARES (14.03 PER CENT). G H R MUSKER COMPANY SECRETARY 22 JANUARY 2004 This information is provided by RNS The company news service from the London Stock Exchange

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AstraZeneca (AZN)
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