Holding(s) in Company

AstraZeneca PLC
11 February 2002

COMPANIES ACT 1985 SECTION 198

DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES

ON 8 FEBRUARY 2002 WE WERE INFORMED BY PUTNAM INVESTMENT MANAGEMENT, LLC AND THE
PUTNAM ADVISORY COMPANY, LLC THAT AS AT 1 FEBRUARY 2002 THEY HAD AN INTEREST IN
THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC OF 52,643,485 SHARES WHICH
REPRESENTS 3.02 PER CENT OF THE ISSUED ORDINARY CAPITAL.  PUTNAM INVESTMENT
MANAGEMENT, LLC AND THE PUTNAM ADVISORY COMPANY, LLC ARE REGISTERED INVESTMENT
ADVISORS IN THE UNITED STATES.

G H R MUSKER

COMPANY SECRETARY

11 FEBRUARY 2002



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