Holding(s) in Company

AstraZeneca PLC
7 May 2002



COMPANIES ACT 1985 SECTION 198

DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES



ON 7 MAY 2002 WE WERE INFORMED BY THE CAPITAL GROUP COMPANIES, INC., A
REGISTERED INVESTMENT MANAGER IN THE U.S., THAT ON 2 MAY 2002 ITS INTEREST IN
THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC HAD INCREASED TO 209,024,956
SHARES (12.02 PER CENT OF THE ISSUED ORDINARY CAPITAL) FROM THE PREVIOUSLY
NOTIFIED LEVEL OF 193,668,081 SHARES (11.00 PER CENT).



G H R MUSKER
COMPANY SECRETARY
7 MAY 2002



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