Holding(s) in Company

AstraZeneca PLC
11 February 2004





COMPANIES ACT 1985 SECTION 198

DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES



WE WERE INFORMED TODAY BY INVESTOR AB THAT ON 10 FEBRUARY 2004 IT REDUCED ITS
HOLDING IN THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC TO 63,465,810 SHARES
WHICH REPRESENTS 3.75 PER CENT OF THE CURRENT ISSUED ORDINARY CAPITAL OF THE
COMPANY.





G H R MUSKER

COMPANY SECRETARY

11 FEBRUARY 2004


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