Holding(s) in Company

AstraZeneca PLC
28 July 2004

COMPANIES ACT 1985 SECTION 198

DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES



ON 27 JULY 2004, WE WERE INFORMED BY WELLINGTON MANAGEMENT COMPANY, LLP, A
REGISTERED INVESTMENT ADVISOR IN THE US, THAT IT HAS A NOTIFIABLE INTEREST IN
THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC OF 53,510,141 SHARES WHICH
REPRESENTS 3.20 PER CENT OF THE ISSUED ORDINARY CAPITAL OF THE COMPANY.





G H R MUSKER
COMPANY SECRETARY
28 JULY 2004




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