Publication of Prospectus

AstraZeneca PLC
14 March 2008

Publication of Supplementary Prospectus

The following supplementary prospectus has been approved by the UK Listing 
Authority and is available for viewing:

Supplementary Prospectus for the AstraZeneca PLC U.S.$5,000,000,000 Euro Medium 
Term Note Programme (the Supplementary Prospectus).

To view the full Supplementary Prospectus, please paste the following URL into 
the address bar of your browser.

http://www.rns-pdf.londonstockexchange.com/rns/2004q_-2008-3-14.pdf

The Supplementary Prospectus and the documents incorporated by reference therein 
are available to the public for inspection at the following addresses:

Document Viewing Facility
UK Listing Authority
25 The North Colonnade
Canary Wharf
London E14 5HS

AstraZeneca PLC
15 Stanhope Gate
London W1K 1LN


G H R Musker
Company Secretary
14 March 2008



                      This information is provided by RNS
            The company news service from the London Stock Exchange