Publication of Prospectus

AstraZeneca PLC 10 September 2007 Publication of Prospectus AstraZeneca PLC has published a prospectus dated 10 September 2007 in respect of its US$5,000,000,000 Euro Medium Term Note Programme. To view the full prospectus, please paste the URL below into the address bar of your browser. http://www.rns-pdf.londonstockexchange.com/rns/6264d_-2007-9-10.pdf One of the documents incorporated by reference into the prospectus has not previously been published by AstraZeneca PLC; in order to view this document, please paste the URL below into the address bar of your browser. http://www.sec.gov/Archives/edgar/data/873591/000110465907014449/a07-5178_310k.htm G H R Musker Company Secretary 10 September 2007 Please note that the prospectus contains restrictions on the sale of the securities described therein to persons in certain jurisdictions and that the prospectus is not addressed to such persons, nor should such persons use or rely on the information contained therein. This information is provided by RNS The company news service from the London Stock Exchange

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AstraZeneca (AZN)
UK 100

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