Research Update

AstraZeneca PLC 19 October 2001 ZD1839 IRESSA DATA AstraZeneca is encouraged by the positive results from IDEAL 1 (IRESSA Dose Evaluation in Advanced Lung cancer), the first pivotal study of ZD1839 (IRESSA) in non-small-cell-lung-cancer (NSCLC) and looks forward to the presentation of these phase II data at the 12th AACR-NCI-EORTC International Conference on 'Molecular Targets and Cancer Therapeutics' in Miami, USA. Whilst the abstract of the data is available on www.AACR.org, the full results from IDEAL 1 will not be presented until Thursday, November 1, 2001, and the requirements of the AACR-NCI-EORTC scientific committee preclude discussion of the data presented in the abstract by the authors or the company until the day of the presentation. AstraZeneca will be issuing press information announcing the results from IDEAL I on Thursday, November 1, 2001. IRESSA is a trademark of the AstraZeneca group of companies. Date: October 19, 2001 Media Relations: Steve Brown, Tel: +44 (0) 20 7304 5033 Emily Denney, Tel: +44 (0) 20 7304 5034 Investor Relations: Mina Blair-Robinson, Tel: +44 (0) 20 7304 5084 Jorgen Winroth, Tel: +1 609 896 4148 - Ends -

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