Statement re Zoladex

AstraZeneca PLC 23 June 2003 Stock Exchange Announcement ASTRAZENECA ANNOUNCES SETTLEMENT WITH U.S. GOVERNMENT ON ZOLADEX(R) INVESTIGATION AstraZeneca today announced the settlement of a multi-year investigation into US sales and marketing practices for Zoladex(R) (goserelin acetate implant), a treatment for prostate cancer. Under the terms of the settlement, AstraZeneca Pharmaceuticals LP will admit to having violated the Prescription Drug Marketing Act by providing free samples of Zoladex(R) to physicians during the period 1993 through 1996, with the understanding that these physicians would bill Medicare for reimbursement. AstraZeneca will also settle, without admitting liability, civil claims involving allegations that the Company provided inducements to physicians to purchase Zoladex(R) and for improperly setting and reporting its price. The settlement also provides for a five-year Corporate Integrity Agreement with the Office of Inspector General (OIG) for the Department of Health and Human Services under which AstraZeneca Pharmaceuticals LP is required, among other obligations, to keep in place its current Compliance Program and provide periodic reports to the OIG on the status of compliance activities. AstraZeneca understands that the government investigation is closed, all outstanding issues related to the investigation are resolved and no indictments of current or former employees are expected. The total payment associated with the negotiated settlement is $354,900,000. This amount includes funds set aside to cover individual settlement agreements with the states involving related claims. The company previously announced that it set aside $350,000,000 to cover these settlement costs in its 2002 Annual Results and subsequently in the 20-F filing with the U.S. Securities and Exchange Commission. - Ends - June 23, 2003 Investor Relations: Mina Blair-Robinson, +44 (0) 207 304 5084 Jonathan Hunt, +44 (0) 207 304 5087 Ed Seage (US IR contact), +1 302 886 4065 This information is provided by RNS The company news service from the London Stock Exchange

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