Stmnt re Lawsuit

AstraZeneca PLC 23 April 2001 ASTRAZENECA FILES LAWSUIT AGAINST APOTEX CORPORATION AND TORPHARM FOR PATENT INFRINGEMENT AstraZeneca confirmed today that it has filed a lawsuit in Illinois against Apotex Corporation and Torpharm for patent infringement. The lawsuit is the result of an Abbreviated New Drug Application (ANDA) filed by Torpharm with the Food and Drug Administration (FDA) concerning its intent to market a generic omeprazole product in the US. The antisecretory drug omeprazole is marketed in the US by AstraZeneca, L.P. under the brand name Prilosec and is marketed internationally by AstraZeneca as Losec. The basis for AstraZeneca's complaint is that the action by Torpharm infringes at a minimum formulation patents for Prilosec, the omeprazole sulphenamides patent and patents relating to the treatment of H.Pylori infections. AstraZeneca intends to fully enforce its patent rights and is steadfast in its belief that all the patents are valid. 23 April 2001 Further enquires to: Media Enquiries: Chris Major, Tel: +44 (0)20 7304 5028 Investor Relations: Michael Olsson, Tel: +44 (0)20 7304 5087

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