Total Voting Rights

AstraZeneca PLC
02 January 2008


Transparency Directive
Voting Rights and Capital


The following notification is made in accordance with the UK Financial Services
Authority Disclosure and Transparency Rule 5.6.1.  On 31 December 2007, the
issued share capital of AstraZeneca PLC with voting rights is 1,457,000,853
ordinary shares of US$0.25.  No shares are held in Treasury. Therefore, the
total number of voting rights in AstraZeneca PLC is 1,457,000,853.

The above figure for the total number of voting rights may be used by
shareholders as the denominator for the calculations by which they will
determine if they are required to notify their interest in, or a change to their
interest in, AstraZeneca PLC under the FSA's Disclosure and Transparency Rules.



G H R Musker
Company Secretary
2 January 2008






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