Transaction in Own Shares

AstraZeneca PLC
27 September 2004



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 24 September 2004, it purchased for
cancellation 400,000 ordinary shares of AstraZeneca PLC at a price of 2344 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,661,540,800.



G H R Musker
Company Secretary
27 September 2004


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