Transaction in Own Shares

AstraZeneca PLC
28 September 2004

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 27 September 2004, it purchased for
cancellation 500,000 ordinary shares of AstraZeneca PLC at a price of 2317 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,661,040,800.

G H R Musker
Company Secretary
28 September 2004


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