Transaction in Own Shares

AstraZeneca PLC
21 September 2004



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 20 September 2004, it purchased for
cancellation 750,000 ordinary shares of AstraZeneca PLC at a price of 2321 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,663,290,800.



G H R Musker
Company Secretary
21 September 2004




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