Transaction in Own Shares

AstraZeneca PLC
23 August 2006



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 22 August 2006, it purchased for cancellation
750,000 ordinary shares of AstraZeneca PLC at a price of 3330 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,560,253,425.


G H R Musker
Company Secretary
23 August 2006

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