Transaction in Own Shares

AstraZeneca PLC
29 June 2007


   ASTRAZENECA PLC IRREVOCABLE, NON-DISCRETIONARY SHARE REPURCHASE PROGRAMME

AstraZeneca PLC today announced that it will commence an irrevocable,
non-discretionary programme with Barclays Bank PLC to purchase ordinary shares
on its own behalf during the period which commences on 2 July 2007 and ends on
31 October 2007, therefore running through its two close periods which commence
on 1 July 2007 ending 26 July 2007 and commence 1 October 2007 ending 1 November
2007. Any purchases will be made within certain pre-set parameters and in
accordance with both AstraZeneca PLC's general authority to repurchase shares
and the Listing Rules.

G H R Musker
Company Secretary
29 June 2007


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