Transaction in Own Shares

AstraZeneca PLC
24 August 2005



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 23 August 2005, it purchased for cancellation
1,000,000 ordinary shares of AstraZeneca PLC at a price of 2551 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,607,914,100.


G H R Musker
Company Secretary
24 August 2005




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