Transaction in Own Shares

AstraZeneca PLC
31 August 2005


                        REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 30 August 2005, it purchased for cancellation
900,000 ordinary shares of AstraZeneca PLC at a price of 2526 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,606,024,662.



G H R Musker
Company Secretary
31 August 2005



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