Transaction in Own Shares

AstraZeneca PLC
05 September 2005

REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 2 September 2005, it purchased for
cancellation 500,000 ordinary shares of AstraZeneca PLC at a price of 2581 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,605,594,947.







G H R Musker

Company Secretary

5 September 2005


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