Transaction in Own Shares

AstraZeneca PLC
05 April 2007











REPURCHASE OF SHARES IN ASTRAZENECA PLC





Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 5 February 2007 to 30 April 2007,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 308,404 ordinary shares of AstraZeneca PLC at a price of 2743
pence per share on 4 April 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,510,991,754.





G H R Musker

Company Secretary

5 April 2007


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