Transaction in Own Shares

AstraZeneca PLC
12 April 2007



REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 5 February 2007 to 30 April 2007,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 310,143 ordinary shares of AstraZeneca PLC at a price of 2727
pence per share on 11 April 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,510,143,253.





G H R Musker

Company Secretary

12 April 2007


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