Transaction in Own Shares

AstraZeneca PLC
07 September 2005


                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 6 September 2005, it purchased for
cancellation 550,000 ordinary shares of AstraZeneca PLC at a price of 2611 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,605,153,375.

G H R Musker
Company Secretary
7 September 2005


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