Transaction in Own Shares

AstraZeneca PLC
12 October 2007


REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 222,013 ordinary shares of AstraZeneca PLC at a price of 2586 pence
per share on 11 October 2007. Upon the cancellation of these shares, the number
of shares in issue will be 1,472,135,397.



G H R Musker
Company Secretary
12 October 2007


                      This information is provided by RNS
            The company news service from the London Stock Exchange