Transaction in Own Shares

AstraZeneca PLC
25 September 2006



REPURCHASE OF SHARES IN ASTRAZENECA PLC



AstraZeneca PLC announced that on 22 September 2006, it purchased for
cancellation 600,000 ordinary shares of AstraZeneca PLC at a price of 3322 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,552,263,004.




G H R Musker
Company Secretary

25 September 2006


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