Transaction in Own Shares

AstraZeneca PLC
02 February 2007



ASTRAZENECA PLC IRREVOCABLE, NON-DISCRETIONARY SHARE REPURCHASE PROGRAMME



AstraZeneca PLC today announced that it will commence an irrevocable,
non-discretionary programme with Barclays Bank PLC to purchase ordinary shares
on its own behalf during the period 5 February 2007 to 30 April 2007.



Any purchases will be effected within certain pre-set parameters and in
accordance with both AstraZeneca PLC's general authority to repurchase shares
and the Listing Rules.







G H R Musker
Company Secretary
2 February 2007


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