Transaction in Own Shares

AstraZeneca PLC
27 September 2006



REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 26 September 2006, it purchased for
cancellation 750,000 ordinary shares of AstraZeneca PLC at a price of 3313 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,551,559,697.







G H R Musker

Company Secretary

27 September 2006


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