Transaction in Own Shares

AstraZeneca PLC
03 October 2006




                   REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its close period share repurchase programme,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 393,451 ordinary shares of AstraZeneca PLC at a price of 3344
pence per share on 2 October 2006. Upon the cancellation of these shares, the
number of shares in issue will be 1,550,434,585.





G H R Musker
Company Secretary
3 October 2006


                      This information is provided by RNS
            The company news service from the London Stock Exchange