Transaction in Own Shares

AstraZeneca PLC
12 February 2007


                   REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 5 February 2007 to 30 April 2007,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 289,089 ordinary shares of AstraZeneca PLC at a price of 2931
pence per share on 9 February 2007.

In addition, AstraZeneca PLC announced that on the same date, it purchased for
cancellation 500,000 ordinary shares of AstraZeneca PLC at a price of 2929 pence
per share.

Upon the cancellation of all of the shares purchased on that date, the number of
shares in issue will be 1,530,571,645.


G H R Musker
Company Secretary
12 February 2007


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