Transaction in Own Shares

AstraZeneca PLC
09 October 2006


                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its close period share repurchase programme,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 396,861 ordinary shares of AstraZeneca PLC at a price of 3315
pence per share on 6 October 2006. Upon the cancellation of these shares, the
number of shares in issue will be 1,548,929,846.


G H R Musker
Company Secretary
9 October 2006


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