Transaction in Own Shares

AstraZeneca PLC
12 October 2006



REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its close period share repurchase programme,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 399,294 ordinary shares of AstraZeneca PLC at a price of 3295
pence per share on 11 October 2006. Upon the cancellation of these shares, the
number of shares in issue will be 1,547,760,226.







G H R Musker

Company Secretary

12 October 2006


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