Transaction in Own Shares

AstraZeneca PLC
27 November 2007




REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 26 November 2007, it purchased for
cancellation 900,000 ordinary shares of AstraZeneca PLC at a price of 2254 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,460,006,008.



G H R Musker
Company Secretary
27 November 2007


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