Transaction in Own Shares

AstraZeneca PLC
05 November 2007

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 2 November 2007, it purchased for cancellation
1,000,000 ordinary shares of AstraZeneca PLC at a price of 2320 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,467,949,772.


G H R Musker
Company Secretary
5 November 2007


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