Transaction in Own Shares

AstraZeneca PLC
07 August 2007

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 227,041 ordinary shares of AstraZeneca PLC at a price of 2525 pence
per share on 6 August 2007. Upon the cancellation of these shares, the number of
shares in issue will be 1,489,203,716.


G H R Musker
Company Secretary
7 August 2007


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