Transaction in Own Shares

AstraZeneca PLC
18 May 2006



REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 17 May 2006, it purchased for cancellation
1,300,000 ordinary shares of AstraZeneca PLC at a price of 2868 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,573,528,230.







G H R Musker

Company Secretary

18 May 2006


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