Transaction in Own Shares

AstraZeneca PLC
09 November 2007

                     REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 8 November 2007, it purchased for cancellation
900,000 ordinary shares of AstraZeneca PLC at a price of 2202 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,465,300,760.

G H R Musker
Company Secretary
9 November 2007


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