Transaction in Own Shares

AstraZeneca PLC
17 August 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC





AstraZeneca PLC announced that on 16 August 2007, it purchased for cancellation
1,048,161 ordinary shares of AstraZeneca PLC at a price of 2,284 pence per
share.



Some of these shares were purchased under the terms of the previously announced
irrevocable, non-discretionary share repurchase programme for the period 2 July
2007 to 31 October 2007.



Upon the cancellation of these shares, the number of shares in issue will be
1,484,425,401.





G H R Musker

Company Secretary

17 August 2007


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