Transaction in Own Shares

AstraZeneca PLC
01 June 2006

                     REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 31 May 2006, it purchased for cancellation
700,000 ordinary shares of AstraZeneca PLC at a price of 2787 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,569,013,782.







G H R Musker
Company Secretary
1 June 2006


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