Transaction in Own Shares

AstraZeneca PLC
16 November 2007




REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 15 November 2007, it purchased for
cancellation 800,000 ordinary shares of AstraZeneca PLC at a price of 2202 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,463,501,457.


G H R Musker
Company Secretary
16 November 2007


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