Transaction in Own Shares

AstraZeneca PLC
19 November 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC





AstraZeneca PLC announced that on 16 November 2007, it purchased for
cancellation 800,000 ordinary shares of AstraZeneca PLC at a price of 2203 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,462,701,457.





G H R Musker

Company Secretary

19 November 2007


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